Multiple Sclerosis

About Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease affecting the central nervous system. MS is the most common cause of disability in young adults in the UK. Sheffield is a major UK trials centre for new drugs that have revolutionised MS therapy and our researchers are UK leaders for autologous haematopoietic stem-cell transplantation (AHSCT) in MS.

Our aims

In the short term, we aim to establish standardised ways to collect information about patients' symptoms, and samples that can tell us about the underlying disease processes will help towards developing treatments that are more individually tailored in the future.

In the longer term, we aim to develop the Sheffield Bone Marrow Transplantation Programme into a centre of excellence for autologous haematopoietic stem cell transplantation (AHSCT); a new way to treat neuroinflammatory conditions like MS.

Find out more about this treatment on the Sheffield Teaching Hospitals NHS Foundation Trust AHSCT website.


Professor Basil Sharrack

Neuroinflammation Sub Theme Lead

Prof. John Snowden

Dr. David Paling

Prof. Mimoun Azzouz

Prof. Sherif El-Khamisy

Sheffield BRC > Research themes > Neuroscience > Multiple Sclerosis